The Airbus A320 families are low-wing cantilever monoplanes with a conventional tail unit with a single fin and rudder. They have a retractable tricycle landing gear and are powered by two wing mounted turbofan engines. Compared to other airliners of the same class, the A320 features a wider single-aisle cabin of 155.5 inches (3.95 m) outside diameter, compared to 148 inches (3.8 m) in the Boeing 737 and 131.6 inches (3.34 m) in the Boeing 717, and larger overhead bins, along with fly-by-wire technology. In addition, the aircraft has a spacious cargo hold equipped with large doors to assist in expedient loading and unloading of goods.

Technically, the name "A320" only refers to the original mid-sized aircraft, but it is often informally used to indicate any of the A318/A319/A320/A321 family. All variants are able to be ETOPS (Extended-range Twin-engine Operational Performance Standards) certified.